Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma

Fei Li, Wenzhe Si, Li Xia, +7

Molecular Cancer

Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis

Wenzhe Si, Wei Huang, Yu Zheng, +17

Cancer Cell

Breast Cancer MetastasisBreast OncologyMedicineReciprocal Feedback LoopCancer Biology +6

JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation

Feng Wang, Lin He, Peiwei Huangyang, +13

PLoS Biology

Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development

Xiao Han, Bin Gui, Cong Xiong, +17

Molecular Cell

NeuroregenerationMolecular NeuroscienceDevelopmental BiologyJade-2 Promotes NeurogenesisBrain Development +11

JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component

Xujun Liu, Wenzhe Si, Xinhua Liu, +9

Molecular Cancer

The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry

Xujun Liu, Wenzhe Si, Lin He, +20

Signal Transduction and Targeted Therapy

USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair

Ting Xia, Lu Xia, Jianguo Yang, +4

Nucleic Acids Research

Histone ModificationsEpigenetic ChangeGeneticsGenomic MechanismMolecular Biology +18

SET7/9 promotes multiple malignant processes in breast cancer development via RUNX2 activation and is negatively regulated by TRIM21

Wenzhe Si, Jiansuo Zhou, Yang Zhao, +2

Cell Death and Disease

The coordination between ZNF217 and LSD1 contributes to hepatocellular carcinoma progress and is negatively regulated by miR-101

Wenzhe Si, Yang Zhao, Jiansuo Zhou, +2

Experimental Cell Research

Tumor BiologyRadiation OncologyHcc Cell ProliferationOncologyOncogenic Agent +12

SCF^JFK is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer

Ruorong Yan, Lin He, Zhongwu Li, +14

Genes & Development