Mian Zhang

Guide to development of compound files for <scp>PBPK</scp> modeling in the Simcyp population‐based simulator

Udoamaka Ezuruike, Mian Zhang, Amita Pansari et al. · CPT Pharmacometrics & Systems Pharmacology · 2022 · 47 citations · Full text

Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling

Karen Rowland Yeo, Mian Zhang, Xian Pan et al. · Clinical Pharmacology & Therapeutics · 2020 · 40 citations · Full text

Physiologically-based Pharmacokinetic Modeling, Respiratory Disease, Pharmacodynamic Modeling +20

Prediction of CYP‐mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator

Peter Kilford, Kuan‐Fu Chen, Kim Crewe et al. · CPT Pharmacometrics & Systems Pharmacology · 2022 · 38 citations · Full text

Unraveling pleiotropic effects of rifampicin by using physiologically based pharmacokinetic modeling: Assessing the induction magnitude of P‐glycoprotein–cytochrome P450 3A4 dual substrates

Xian Pan, Shinji Yamazaki, Sibylle Neuhoff et al. · CPT Pharmacometrics & Systems Pharmacology · 2021 · 21 citations · Full text