Mitchell Keegan

CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

Cheng-Jung Lai, Rudi Bao, Xu Tao et al. · Cancer Research · 2010 · 212 citations · Full text

Medicine, Oncology, Pharmacology +17

Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer

David E. Gerber, D. Ross Camidge, Daniel Morgensztern et al. · Lung Cancer · 2019 · 182 citations · Full text

Medicine, Oncology, Pharmacology +12

The Novel Combination of Chlorpromazine and Pentamidine Exerts Synergistic Antiproliferative Effects through Dual Mitotic Action

Margaret Lee, Lisa M. Johansen, Yanzhen Zhang et al. · Cancer Research · 2007 · 112 citations

Medicine, Oncology, Pharmacology +17

A first-in-Asian phase 1 study to evaluate safety, pharmacokinetics and clinical activity of VS-6063, a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors

Toshio Shimizu, Kazuya Fukuoka, Masayuki Takeda et al. · Cancer Chemotherapy and Pharmacology · 2016 · 109 citations · Full text

Medicine, Oncology, Pharmacology +16

Increase in β-Cell Mass in Transplanted Porcine Neonatal Pancreatic Cell Clusters Is Due to Proliferation of β-Cells and Differentiation of Duct Cells*

Nitin Trivedi, Jennifer Hollister‐Lock, María Dolores López-Ávalos et al. · Endocrinology · 2001 · 76 citations

Life Sciences, Cell Biology, Endocrinology +15