Cheng-Jung Lai

A frizzled homolog functions in a vertebrate Wnt signaling pathway

Julia Yang-Snyder, Jeffrey R. Miller, Jeffrey D. Brown et al. · Current Biology · 1996 · 472 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Discovery of 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-<i>N</i>-hydroxyheptanamide (CUDC-101) as a Potent Multi-Acting HDAC, EGFR, and HER2 Inhibitor for the Treatment of Cancer

Xiong Cai, Hai-Xiao Zhai, Jing Wang et al. · Journal of Medicinal Chemistry · 2010 · 264 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Changgeng Qian, Cheng-Jung Lai, Rudi Bao et al. · Clinical Cancer Research · 2012 · 241 citations

Medicine, Oncology, Pharmacology +15

Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin

L. Lynn McGrew, Cheng-Jung Lai, Randall T. Moon · Developmental Biology · 1995 · 222 citations

Life Sciences, Developmental Biology, Neurobiology +13

CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

Cheng-Jung Lai, Rudi Bao, Xu Tao et al. · Cancer Research · 2010 · 212 citations · Full text

Medicine, Oncology, Pharmacology +17