Changgeng Qian

GDC-0449—A potent inhibitor of the hedgehog pathway

Kirk Robarge, Shirley A. Brunton, Georgette M. Castanedo et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 385 citations · Full text

Molecular Pharmacology, Signaling Pathway, Molecular Pathway +6

Discovery of 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-<i>N</i>-hydroxyheptanamide (CUDC-101) as a Potent Multi-Acting HDAC, EGFR, and HER2 Inhibitor for the Treatment of Cancer

Xiong Cai, Hai-Xiao Zhai, Jing Wang et al. · Journal of Medicinal Chemistry · 2010 · 258 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Pharmaceutical Chemistry +18

Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Changgeng Qian, Cheng-Jung Lai, Rudi Bao et al. · Clinical Cancer Research · 2012 · 236 citations

CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

Cheng-Jung Lai, Rudi Bao, Xu Tao et al. · Cancer Research · 2010 · 211 citations · Full text

Dermatology, Cancer Biology, Tumor Biology +16

Epibatidine is a nicotinic analgesic

Changgeng Qian, Tongchuan Li, T. Y. Shen et al. · European Journal of Pharmacology · 1993 · 169 citations

Health Sciences, Pain Medicine, Nicotine +8