Toshio Shimizu

E-CELL: software environment for whole-cell simulation.

Masaru Tomita, Kazuaki Hashimoto, Kazutoshi Takahashi et al. · Bioinformatics · 1999 · 765 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Activation of ERBB2 Signaling Causes Resistance to the EGFR-Directed Therapeutic Antibody Cetuximab

Kimio Yonesaka, Kreshnik Zejnullahu, Isamu Okamoto et al. · Science Translational Medicine · 2011 · 670 citations

Medicine, Oncology, Pharmacology +17

The Clinical Effect of the Dual-Targeting Strategy Involving PI3K/AKT/mTOR and RAS/MEK/ERK Pathways in Patients with Advanced Cancer

Toshio Shimizu, Anthony W. Tolcher, Kyriakos P. Papadopoulos et al. · Clinical Cancer Research · 2012 · 432 citations

Medicine, Oncology, Pharmacology +17

Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study

Kuniko Sunami, Hitoshi Ichikawa, Takashi Kubo et al. · Cancer Science · 2019 · 377 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: “waiting for Godot”

Kaoru Azumi, Rosaria De Santis, Anthony De Tomaso et al. · Immunogenetics · 2003 · 294 citations

Life Sciences, Genetics, Immunology +16