Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

Simon G. Gregory, Jessica J. Connelly, Aaron J. Towers, +13

BMC Medicine

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1

Makoto R. Hara, Jeffrey J. Kovacs, Erin J. Whalen, +12

Nature

Reductive StressTranscriptional RegulationDna DamageMolecular PhysiologyStress Hormone +8

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

Li Zhu, Xiaoming Wang, Xinlei Li, +8

Human Molecular Genetics

NeurogenomicsBrain DevelopmentAutism Spectrum DisordersGeneticsDna Methylation +21

Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors

Alexandra L. Bey, Xiaoming Wang, Namsoo Kim, +11

Translational Psychiatry

Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes

Christopher G. Duncan, Patrick Killela, Cathy A. Payne, +11

Oncotarget

Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development

Wenhao Zhang, Weikun Xia, Q. Wang, +17

Molecular Cell

ChromatinLineage PlasticityDevelopmental BiologyIsoform SwitchNatural Sciences +9

Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders

Aaron J. Towers, Martine Tremblay, Leeyup Chung, +14

JCI Insight

Neuropsychiatric DisordersEpigenetic ChangeGeneticsDna MethylationMrna Isoforms +17

Lovastatin suppresses hyperexcitability and seizure in Angelman syndrome model

Leeyup Chung, Alexandra L. Bey, Aaron J. Towers, +3

Neurobiology of Disease

NeurophysiologyVascular PharmacologyPhysiologyNeuropharmacologyPharmacotherapy +4

Parental origin impairment of synaptic functions and behaviors in cytoplasmic FMRP interacting protein 1 (Cyfip1) deficient mice

Leeyup Chung, Xiaoming Wang, Li Zhu, +4

Brain Research

Synaptic PlasticityProtein FunctionDevelopmental BiologyMolecular NeuroscienceSignal Transduction +9

Human centromere repositioning within euchromatin after partial chromosome deletion

Lori L. Sullivan, Kristin A. Maloney, Aaron J. Towers, +2

Chromosome Research

ChromatinChromatin StructurePartial Chromosome DeletionChromatin RemodelingNatural Sciences +7