Patrick Killela

<i>TERT</i> promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

Patrick Killela, Zachary J. Reitman, Yuchen Jiao et al. · Proceedings of the National Academy of Sciences · 2013 · 1.4K citations · Full text

Medicine, Genetics, Oncology +17

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

Hai Yan, Patrick Killela, Zachary J. Reitman et al. · Neuro-Oncology · 2014 · 533 citations · Full text

Medicine, Molecular Genetics, Oncology +15

Mutations in <i>IDH1</i>, <i>IDH2</i>, and in the <i>TERT</i> promoter define clinically distinct subgroups of adult malignant gliomas

Patrick Killela, Christopher J. Pirozzi, Patrick Healy et al. · Oncotarget · 2014 · 260 citations · Full text

Medicine, Oncology, Pathology +12

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

Liwei Zhang, Lee H. Chen, Hong Wan et al. · Nature Genetics · 2014 · 194 citations · Full text

Life Sciences, Genetics, Neuroscience +10

Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation

Dongsheng Huang, Zhaohui Wang, Xujun He et al. · European Journal of Cancer · 2015 · 191 citations · Full text

Medicine, Genetics, Oncology +16