Eleanor A. L. Bagg

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian et al. · EMBO Reports · 2011 · 1K citations · Full text

Histone Modifications, Chromatin, Biochemistry +6

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

Chris Church, Sheena Lee, Eleanor A. L. Bagg et al. · PLoS Genetics · 2009 · 323 citations · Full text

Metabolic Disorder, Genetics, Human Fat Mass +23

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Richard J. Hopkinson, Anthony Tumber, Clarence Yapp et al. · Chemical Science · 2013 · 163 citations · Full text

Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)

Wei Shen Aik, Marina Demetriades, Muhammad K. K. Hamdan et al. · Journal of Medicinal Chemistry · 2013 · 155 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +22

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6

Monica Mantri, T. Krojer, Eleanor A. L. Bagg et al. · Journal of Molecular Biology · 2010 · 92 citations

Crystal Structure, Biochemistry, Natural Sciences +8