Eleanor A. L. Bagg

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian et al. · EMBO Reports · 2011 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

Chris Church, Sheena Lee, Eleanor A. L. Bagg et al. · PLoS Genetics · 2009 · 324 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Richard J. Hopkinson, Anthony Tumber, Clarence Yapp et al. · Chemical Science · 2013 · 164 citations · Full text

Life Sciences, Biochemistry, Pharmacology +7

Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)

Wei Shen Aik, Marina Demetriades, Muhammad K. K. Hamdan et al. · Journal of Medicinal Chemistry · 2013 · 159 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6

Monica Mantri, T. Krojer, Eleanor A. L. Bagg et al. · Journal of Molecular Biology · 2010 · 92 citations

Life Sciences, Biochemistry, Molecular Biology +10