John R. Butler

Enantioselective Total Synthesis of (−)-Kibdelone C

John R. Butler, Chao Wang, Jianwei Bian et al. · Journal of the American Chemical Society · 2011 · 75 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers

Brian Belmontes, Katherine K. Slemmons, Chun Su et al. · Cancer Discovery · 2024 · 70 citations · Full text

Medicine, Oncology, Pharmacology +17

Sulfonamides as Selective Na_V1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Russell F. Graceffa, Alessandro A. Boezio, Jessica Able et al. · Journal of Medicinal Chemistry · 2017 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Studying the roles of W86, E202, and Y337 in binding of acetylcholine to acetylcholinesterase using a combined molecular dynamics and multiple docking approach

Jeremy Kua, Yingkai Zhang, Angelique C. Eslami et al. · Protein Science · 2003 · 58 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Dehydrogenative Coupling to Enable the Enantioselective Total Synthesis of (−)‐Simaomicin α

Yizhong Wang, Chao Wang, John R. Butler et al. · Angewandte Chemie International Edition · 2013 · 29 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13