Marisa Lopez‐Cruzan

Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial

Mitzi M. Gonzales, Valentina R. Garbarino, Tiffany F. Kautz et al. · Nature Medicine · 2023 · 206 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +12

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Randy Strong, Peter C. Reifsnyder, Navasuja Kumar et al. · Aging Cell · 2021 · 105 citations · Full text

Anti-aging, Aging, Human Growth +28

Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

Meenakshi Tiwari, Marisa Lopez‐Cruzan, W. W. Morgan et al. · Journal of Biological Chemistry · 2011 · 72 citations · Full text

Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice

Randy Strong, Richard A. Miller, Catherine Cheng et al. · Aging Cell · 2022 · 60 citations · Full text

Aging, Heterogeneous Mice, Human Growth +20

Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

David Harrison, Randy Strong, Peter C. Reifsnyder et al. · GeroScience · 2023 · 44 citations · Full text