Erik Gjerstad

In Vitro ADME Profiling Using High-Throughput RapidFire Mass Spectrometry: Cytochrome P450 Inhibition and Metabolic Stability Assays

Xiang Wu, Jing Wang, Lory R Tan et al. · SLAS DISCOVERY · 2012 · 65 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Optimization of Subsite Binding to the β5 Subunit of the Human 20S Proteasome Using Vinyl Sulfones and 2-Keto-1,3,4-oxadiazoles:  Syntheses and Cellular Properties of Potent, Selective Proteasome Inhibitors

Robert M. Rydzewski, Leland C. Burrill, Rohan Mendonca et al. · Journal of Medicinal Chemistry · 2006 · 40 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14

Dissecting and Designing Inhibitor Selectivity Determinants at the S1 Site Using an Artificial Ala190 Protease (Ala190 uPA)

B.A. Katz, Christine Luong, Joseph D. Ho et al. · Journal of Molecular Biology · 2004 · 37 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Potent 4-amino-5-azaindole factor VIIa inhibitors

Huiyong Hu, Aleksandr Kolesnikov, Jennifer R. Riggs et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Synthesis of a statistically exhaustive fluorescent peptide substrate library for profiling protease specificity

James E. Sheppeck, Heidi Kar, Luke Gosink et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 29 citations

Life Sciences, Biochemistry, Molecular Biology +12