Rohan Mendonca

Discovery of Selective Irreversible Inhibitors for Bruton’s Tyrosine Kinase

Zhengying Pan, Heleen Scheerens, Shyr‐Jiann Li et al. · ChemMedChem · 2006 · 669 citations

Rheumatoid Disorder, Molecular Pharmacology, Medicinal Chemistry +14

Design and Synthesis of Tri-Ring P₃ Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K

James T. Palmer, Clifford Bryant, Dan-Xiong Wang et al. · Journal of Medicinal Chemistry · 2005 · 94 citations · Full text

Pharmaceutical Science, Sclerostin, Bone Resorption +18

Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors

Janusz J. Kulagowski, Wade Blair, Richard J. Bull et al. · Journal of Medicinal Chemistry · 2012 · 91 citations · Full text

Rheumatology, Medicinal Chemistry, Drug Target +15

A Novel Class of Nonpeptidic Biaryl Inhibitors of Human Cathepsin K

Joël Robichaud, Renata M. Oballa, Peppi Prasit et al. · Journal of Medicinal Chemistry · 2003 · 82 citations · Full text

Sclerostin, Bioorganic Chemistry, Human Cathepsin K +18

Identification of <i>C</i>-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2

Mark Zak, Christopher A. Hurley, Stuart I. Ward et al. · Journal of Medicinal Chemistry · 2013 · 61 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +19