Stefan O. Ochiana

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Tony Taldone, Pallav D. Patel, Maulik Patel et al. · Journal of Medicinal Chemistry · 2013 · 77 citations · Full text

Drug Target, Molecular Biology, Hsp90 Inhibitors Series +19

Ligand deconstruction: Why some fragment binding positions are conserved and others are not

Dima Kozakov, David R. Hall, Stefan Jehle et al. · Proceedings of the National Academy of Sciences · 2015 · 72 citations · Full text

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Hardik Patel, Pallav D. Patel, Stefan O. Ochiana et al. · Journal of Medicinal Chemistry · 2015 · 64 citations · Full text

Structure–activity Relationship, Drug Target, Purine-scaffold Compound Series +24

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species

Hongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes et al. · Cell Reports · 2015 · 61 citations · Full text

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases B1 and B2 as Druggable Targets for African Sleeping Sickness

Nicholas D. Bland, Cuihua Wang, Craig Tallman et al. · Journal of Medicinal Chemistry · 2011 · 53 citations

Drug Target, Antiparasitic Agent, Malaria +17