Francesco Tinazzi

Application of Quality by Design Principles to Support Development of a Control Strategy for the Control of Genotoxic Impurities in the Manufacturing Process of a Drug Substance

Zadeo Cimarosti, Fernando Bravo, P. Stonestreet et al. · Organic Process Research & Development · 2009 · 45 citations

Pharmacy, Toxicology, Pharmaceutical Manufacturing +16

Synthesis of the NK1 Receptor Antagonist GW597599. Part 1: Development of a Scalable Route to a Key Chirally Pure Arylpiperazine

Giuseppe Guercio, Sergio Bacchi, Michael Goodyear et al. · Organic Process Research & Development · 2008 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Application of the QbD Principles in the Development of the Casopitant Mesylate Manufacturing Process. Process Research Studies for the Definition of the Control Strategy of some Drug Substance-CQAs for Stages 2a, 2b, and 2c

Zadeo Cimarosti, Fernando Bravo, Damiano Castoldi et al. · Organic Process Research & Development · 2010 · 26 citations

Pharmacy, Pharmacology, Regulatory Pharmacy +17

Synthesis of the NK1 Receptor Antagonist GW597599. Part 3: Development of a Scalable Route to a Key Chirally Pure Arylpiperazine Urea, A Happy End

Giuseppe Guercio, Sergio Bacchi, Alcide Perboni et al. · Organic Process Research & Development · 2009 · 16 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Development of a Dynamic Kinetic Resolution for the Isolation of an Intermediate in the Synthesis of Casopitant Mesylate: Application of QbD Principles in the Definition of the Parameter Ranges, Issues in the Scale-Up and Mitigation Strategies

Fernando Bravo, Zadeo Cimarosti, Francesco Tinazzi et al. · Organic Process Research & Development · 2010 · 13 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +17