X‐ray Diffraction and Theoretical Studies for the Quantitative Assessment of Intermolecular Arene–Perfluoroarene Stacking Interactions

Sergio Bacchi, Maurizio Benaglia, Franco Cozzi, +3

Chemistry - A European Journal

EngineeringComputational ChemistryChemistryInterface ChemistryRecognition Motif +14

Synthesis, X‐ray Diffraction and Computational Study of the Crystal Packing of Polycyclic Hydrocarbons Featuring Aromatic and Perfluoroaromatic Rings Condensed in the Same Molecule: 1,2,3,4‐Tetrafluoronaphthalene, ‐anthracene and ‐phenanthrene

Franco Cozzi, Sergio Bacchi, G. Filippini, +2

Chemistry - A European Journal

EngineeringOrganic ChemistryComputational ChemistryChemistrySame Molecule +17

Highly efficient and safe procedure for the synthesis of aryl 1,2,3-triazoles from aromatic amine in a continuous flow reactor

Federica Stazi, Damiano Cancogni, Lucilla Turco, +2

Tetrahedron Letters

EngineeringAromatic AmineSafe ProcedureOrganic ChemistryFlow Synthesis +3

Synthesis of the NK1 Receptor Antagonist GW597599. Part 1: Development of a Scalable Route to a Key Chirally Pure Arylpiperazine

Giuseppe Guercio, Sergio Bacchi, Michael Goodyear, +3

Organic Process Research & Development

Combinatorial ChemistryBioorganic ChemistryArylpiperazine Derivative 7Organic ChemistryPharmaceutical Chemistry +14

Competition between hydrogen bonding and arene–perfluoroarene stacking. X-Ray diffraction and molecular simulation on 5,6,7,8-tetrafluoro-2-naphthoic acid and 5,6,7,8-tetrafluoro-2-naphthamide crystals

Franco Cozzi, Sergio Bacchi, G. Filippini, +2

CrystEngComm

X-ray CrystallographyEngineeringNatural SciencesChemical BondX-ray Diffraction +13

Identification of a Manufacturing Route of Novel CRF-1 Antagonists Containing a 2,3-Dihydro-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine Moiety

Arianna Ribecai, Sergio Bacchi, Monica Delpogetto, +9

Organic Process Research & Development

Combinatorial ChemistryBioorganic ChemistryOrganic ChemistryChemistryHeterocycle Chemistry +14

Reversal of stereochemistry in a two-step Staudinger reaction by changing the backbone protecting group. Synthesis of NH-trans-3-benzoyloxy-4-aryl-azetidinones

Mauro Panunzio, Sergio Bacchi, Eileen Campana, +2

Tetrahedron Letters

EngineeringTwo-step Staudinger ReactionOrganic ChemistryStereoselective SynthesisChemistry +3

A Mechanistic Insight into a Simple C−N Bond Formation via S_N2 Displacement: A Synergistic Kinetics and Design of Experiment Approach

Luca Massari, Laura Panelli, Mark Hughes, +5

Organic Process Research & Development

Combinatorial ChemistryDescriptive Kinetic ModelMechanistic InsightChemistryHeterocycle Chemistry +18

Synthesis of the NK1 Receptor Antagonist GW597599. Part 2: Development of a Scalable Route to a Key Chirally Pure Arylpiperazine

Giuseppe Guercio, Angelo M. Manzo, Michael Goodyear, +3

Organic Process Research & Development

Combinatorial ChemistryMolecular PharmacologyMedicinal ChemistrySecond StageBioorganic Chemistry +13

Highly <i>syn</i>-Diastereoselective Synthesis of <i>NH</i>-3-Benzyloxy-4-aryl-azetidin-2-ones via a Two-Step Staudinger Reaction

Sergio Bacchi, Alessandro Bongini, Mauro Panunzio, +1

Synlett

Asymmetric CatalysisEnantioselective SynthesisEngineeringTwo-step Staudinger ReactionOrganic Chemistry +7