Giuseppe Guercio

Mild and convenient one-pot synthesis of 1,3,4-oxadiazoles

Paolo Stabile, Alessandro Lamonica, Arianna Ribecai et al. · Tetrahedron Letters · 2010 · 69 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Discovery Process and Pharmacological Characterization of 2-(<i>S</i>)-(4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-(<i>R</i>)-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide (Vestipitant) as a Potent, Selective, and Orally Active NK₁ Receptor Antagonist

Romano Di Fabio, Cristiana Griffante, Giuseppe Alvaro et al. · Journal of Medicinal Chemistry · 2009 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Biological Characterization of (2<i>R</i>,4<i>S</i>)-1′-Acetyl-<i>N</i>-{(1<i>R</i>)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-<i>N</i>-methyl-4,4′-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK₁) Receptor Antagonist Clinical Candidate

Romano Di Fabio, Giuseppe Alvaro, Cristiana Griffante et al. · Journal of Medicinal Chemistry · 2011 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Synthesis of the NK1 Receptor Antagonist GW597599. Part 1: Development of a Scalable Route to a Key Chirally Pure Arylpiperazine

Giuseppe Guercio, Sergio Bacchi, Michael Goodyear et al. · Organic Process Research & Development · 2008 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Reaction of dianions of acyclic .beta.-enamino ketones with electrophiles. 3. Nitriles: synthesis of pyridine and pyrimidine derivatives

Giuseppe Bartoli, Marcella Bosco, Cristina Cimarelli et al. · The Journal of Organic Chemistry · 1992 · 20 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13