JoAnne McLaurin

Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model

JoAnne McLaurin, Meredith E. Kierstead, Mary E. Brown et al. · Nature Medicine · 2006 · 361 citations

Molecular Pharmacology, Neurodegenerative Diseases, Alzheimer's Disease +13

Hippocampal GABAergic Neurons are Susceptible to Amyloid-β Toxicity in vitro and are Decreased in Number in the Alzheimer's Disease TgCRND8 Mouse Model

Slavica Krantic, Nathalie Isorce, Naguib Mechawar et al. · Journal of Alzheimer s Disease · 2012 · 75 citations

Tgcrnd8 Mice, Synaptic Transmission, Neurochemical Biomarkers +21

Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation

Yedi Sun, Guohua Zhang, Cheryl A. Hawkes et al. · Bioorganic & Medicinal Chemistry · 2008 · 66 citations

Scyllo-inositol Derivatives, Biochemistry, Natural Sciences +5

Tau follows principal axes of functional and structural brain organization in Alzheimer’s disease

Julie Ottoy, Min Su Kang, Jazlynn Xiu Min Tan et al. · Nature Communications · 2024 · 38 citations · Full text

Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer’s disease

Mingzhe Liu, Stefan D. Jevtic, Kelly Markham-Coultes et al. · Brain Research · 2017 · 32 citations

Neurodegenerative Diseases, Combination Aβ-targeted Treatment, Alzheimer's Disease +12