ASPP2 Binds Par-3 and Controls the Polarity and Proliferation of Neural Progenitors during CNS Development

Roberta Sottocornola, Christophe Royer, Virginie Vives, +10

Developmental Cell

NeuroregenerationMolecular NeuroscienceSignal TransductionDevelopmental BiologyBrain Development +12

Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers

Emilie A. Chapeau, Laurent Sansregret, Giorgio Giacomo Galli, +28

Nature Cancer

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity

Paola Di Stefano, Laura Damiano, Sara Cabodi, +10

The EMBO Journal

Tumor BiologyCell PropertiesSignal TransductionSignaling PathwayCell Regulation +11

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Martin Schröder, Martin Renatus, Xiaoyou Liang, +37

Nature Communications

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

Melusine Bleu, Swann Gaulis, Rui Lopes, +16

Nature Communications

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

Luca Tordella, Sadaf Khan, Anja Hohmeyer, +13

Genes & Development

p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation

Laura Damiano, P Di Stefano, Maria Pilar Camacho Leal, +10

Oncogene

Cancer ResearchSignaling PathwayE-cadherin/egfr Cross-talkMedicineReceptor Tyrosine Kinase +8

ASPP2 suppresses squamous cell carcinoma via RelA/p65–mediated repression of p63

Luca Tordella, Sofia Koch, Victoria Salter, +14

Proceedings of the National Academy of Sciences

Structure of the MRAS–SHOC2–PP1C phosphatase complex

Zachary J. Hauseman, Michelle Fodor, Anxhela Dhembi, +21

Nature

Therapeutic Assessment of Targeting ASNS Combined with <scp>l</scp> -Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms

Verena Apfel, Damien Bégué, Valentina Cordo’, +14

ACS Pharmacology & Translational Science