J.R. Riordan

Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.

Gergely L. Lukács, Asmaa Mohamed, Norbert Kartner et al. · The EMBO Journal · 1994 · 397 citations · Full text

Molecular Physiology, Natural Sciences, Conformational Maturation +13

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

Gergely L. Lukács, X.B. Chang, Christine E. Bear et al. · Journal of Biological Chemistry · 1993 · 386 citations · Full text

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.

S. Pind, J.R. Riordan, Donald B. Williams · Journal of Biological Chemistry · 1994 · 355 citations · Full text

Molecular Biology, Cellular Physiology, Af508 Cftr +16

Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA

J.R. Riordan · Trends in Genetics · 1989 · 334 citations

Cystic Fibrosis Gene, Molecular Diagnostic Techniques, Complementary Dna +11

Mapping of cystic fibrosis transmembrane conductance regulator membrane topology by glycosylation site insertion

Xiaowei Chang, Yanming Hou, Timothy J. Jensen et al. · Journal of Biological Chemistry · 1994 · 133 citations · Full text

Membrane Structure, Proteinlipid Interaction, Membrane Topology +20