Joseph M. Metzger

An integrative genomics approach to infer causal associations between gene expression and disease

Eric E. Schadt, John R. Lamb, Xia Yang et al. · Nature Genetics · 2005 · 1K citations · Full text

Genome-wide Association Study, Causal Associations, Epidemiology +15

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

Airu S. Chen, Donald J. Marsh, Myrna E. Trumbauer et al. · Nature Genetics · 2000 · 891 citations

Obesity, Metabolic Syndrome, Energy Homeostasis +9

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

Donald J. Marsh, Drew T. Weingarth, Dawn E. Novi et al. · Proceedings of the National Academy of Sciences · 2002 · 546 citations · Full text

Metabolic Rate, Gastrointestinal Peptide Hormone, Obesity +19

11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

Anne Hermanowski‐Vosatka, James M. Balkovec, Kang Cheng et al. · The Journal of Experimental Medicine · 2005 · 362 citations · Full text

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-<i>t</i>-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

John W. Gillard, A W Ford‐Hutchinson, Chi-Chung Chan et al. · Canadian Journal of Physiology and Pharmacology · 1989 · 328 citations