Paul Spurr

Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines

Ιoannis V. Pavlidis, Martin S. Weiß, Maika Genz et al. · Nature Chemistry · 2016 · 235 citations

Asymmetric Catalysis, Engineering, Asymmetric Synthesis +7

"Pagodane": the efficient synthesis of a novel, versatile molecular framework

Wolf Dieter Fessner, Gottfried Sedelmeier, Paul Spurr et al. · Journal of the American Chemical Society · 1987 · 144 citations

Combinatorial Chemistry, Engineering, Chemical Analysis +18

New, Efficient Synthesis of Oseltamivir Phosphate (Tamiflu) via Enzymatic Desymmetrization of a <i>meso</i>-1,3-Cyclohexanedicarboxylic Acid Diester

Ulrich Zutter, Hans Iding, Paul Spurr et al. · The Journal of Organic Chemistry · 2008 · 95 citations

Pig Liver Esterase, Oseltamivir Phosphate 1, Efficient Synthesis +18

Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators: Discovery of 2-Chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1<i>H</i>-imidazol-4-ylethynyl]pyridine (Basimglurant, RO4917523), a Promising Novel Medicine for Psychiatric Diseases

Georg Jaeschke, Sabine Kolczewski, Will Spooren et al. · Journal of Medicinal Chemistry · 2015 · 63 citations · Full text

Psychotropic Medication, Psychopharmacology, Pharmacotherapy +19

Amine Transaminase Engineering for Spatially Bulky Substrate Acceptance

Martin S. Weiß, Ιoannis V. Pavlidis, Paul Spurr et al. · ChemBioChem · 2017 · 55 citations

Amine Transaminase, Engineering, Molecular Biology +16