Kaitlyn Le

Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3

Ethan V. Abel, Kevin J. Basile, Curtis H. Kugel et al. · Journal of Clinical Investigation · 2013 · 236 citations · Full text

Enhanced Erbb3, Medicine, Melanoma +11

Selective <scp>RAF</scp> inhibitor impairs <scp>ERK</scp>1/2 phosphorylation and growth in mutant <scp>NRAS</scp>, vemurafenib‐resistant melanoma cells

Kaitlyn Le, Erik Blomain, Ulrich Rodeck et al. · Pigment Cell & Melanoma Research · 2013 · 67 citations · Full text

Cancer Research, Health Sciences, Medicine +15

BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association

Michael J. Vido, Kaitlyn Le, Edward J. Hartsough et al. · Cell Reports · 2018 · 51 citations · Full text

Inhibition of mutant <scp>BRAF</scp> splice variant signaling by next‐generation, selective <scp>RAF</scp> inhibitors

Kevin J. Basile, Kaitlyn Le, Edward J. Hartsough et al. · Pigment Cell & Melanoma Research · 2014 · 50 citations · Full text

NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma

Yongping Shao, Kaitlyn Le, Hanyin Cheng et al. · Journal of Investigative Dermatology · 2015 · 21 citations · Full text

Medicine, Nf-κb Regulation, Immunology +8