PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression

Kim H.T. Paraiso, Yun Xiang, Vito W. Rebecca, +13

Cancer Research

Cancer ResearchCell RegulationMedicineApoptosisPten Expression +13

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

Marta Herreros‐Villanueva, Zhang Js, Alexander Köenig, +8

Oncogenesis

Cell-like FeaturesCancer Stem CellPancreatic Cancer CellsCancer BiologyTumor Biology +15

Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma

Edward Kim, Vaibhav Sahai, Ethan V. Abel, +9

Clinical Cancer Research

Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3

Ethan V. Abel, Kevin J. Basile, Curtis H. Kugel, +11

Journal of Clinical Investigation

Enhanced Erbb3MedicineMelanomaCancer GenomicsCancer Biology +9

GM-CSF Mediates Mesenchymal–Epithelial Cross-talk in Pancreatic Cancer

Meghna Waghray, Malica Yalamanchili, Michele Dziubinski, +13

Cancer Discovery

The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer

Ethan V. Abel, Edward Kim, Jingjiang Wu, +6

PLoS ONE

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

Michele B. Weiss, Ethan V. Abel, Melanie M. Mayberry, +3

Cancer Research

Mcl-1 Is Required for Melanoma Cell Resistance to Anoikis

Karen Boisvert-Adamo, Whitney Longmate, Ethan V. Abel, +1

Molecular Cancer Research

FOXD3 Is a Mutant B-RAF–Regulated Inhibitor of G1-S Progression in Melanoma Cells

Ethan V. Abel, Andrew E. Aplin

Cancer Research

Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells

Inna V. Fedorenko, Ethan V. Abel, John M. Koomen, +13

Oncogene

Braf Inhibitor ResponseMedicineMelanomaFibronectin InductionImmune Checkpoint Inhibitor +6