Francisco Estévez-Sarmiento

Design, synthesis, <i>in vitro</i> antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach

Delia Preti, Romeo Romagnoli, Riccardo Rondanin et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 22 citations · Full text

3′-Hydroxy-3,4′-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells

Francisco Estévez-Sarmiento, Mercedes Said, Ignacio Brouard et al. · Bioorganic & Medicinal Chemistry · 2017 · 16 citations

Medicine, Melanoma, Immunology +9

Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells

Francisco Estévez-Sarmiento, Ester Saavedra, Mercedes Ruíz-Estévez et al. · International Journal of Molecular Sciences · 2020 · 16 citations · Full text

Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells

Romeo Romagnoli, Filippo Prencipe, Paola Oliva et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 13 citations · Full text

3′-Hydroxy-3,4′-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK

Francisco Estévez-Sarmiento, E Vidana Hernandez, Ignacio Brouard et al. · Chemico-Biological Interactions · 2018 · 13 citations

Inflammation, Redox Signaling, 3′-Hydroxy-3,4′-dimethoxyflavone-induced Cell Death +12