Jos Domen

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Tannishtha Reya, Andrew W. Duncan, Laurie Ailles et al. · Nature · 2003 · 2.1K citations

Developmental Biology, Haematopoietic Stem Cells, Medicine +7

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

N M van der Lugt, Jos Domen, Koert Linders et al. · Genes & Development · 1994 · 778 citations · Full text

Bmi-1 Gene, B-cell Lymphomagenesis, Genetics +19

Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

Maarten van Lohuizen, Sjef Verbeek, Paul Krimpenfort et al. · Cell · 1989 · 496 citations

Lymphoid Neoplasia, Pim-1 Transgenic Mice, Oncogenic Agent +6

The Role of Apoptosis in the Regulation of Hematopoietic Stem Cells

Jos Domen, Samuel Cheshier, Irving L. Weissman · The Journal of Experimental Medicine · 2000 · 333 citations · Full text

The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.

Chris Saris, Jos Domen, Anton Berns · The EMBO Journal · 1991 · 302 citations · Full text

Signal Transduction, Related Protein-serine/threonine Kinases, Signaling Pathway +10