Anton Berns

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell · 1994 · 2.3K citations

Medicine, Pharmacokinetics, Pharmacology +14

Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Jasper Smit, Alfred H. Schinkel, Ronald P.J. Oude Elferink et al. · Cell · 1993 · 1.5K citations

Medicine, Molecular Genetics, Pharmacology +16

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

Jacqueline J.L. Jacobs, Blanca Scheijen, Jan Willem Voncken et al. · Genes & Development · 1999 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Requirement for a functional Rb-1 gene in murine development

Alan R. Clarke, Els Robanus Maandag, M van Roon et al. · Nature · 1992 · 1K citations

Life Sciences, Developmental Biology, Genetics +6

Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging

Maarten van Lohuizen, Sjef Verbeek, Blanca Scheljen et al. · Cell · 1991 · 771 citations

Medicine, Genetics, Molecular Biology +14