Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice

Kotaro Kumagai, Kazuaki Tabu, Fumisato Sasaki, +11

PLoS ONE

Pathogenic Mutation of ALK2 Inhibits Induced Pluripotent Stem Cell Reprogramming and Maintenance: Mechanisms of Reprogramming and Strategy for Drug Identification

Makoto Hamasaki, Yoshinobu Hashizume, Yoshinori Yamada, +8

Stem Cells

Pathogenic MutationInduced Pluripotent Stem CellDrug IdentificationDevelopmental BiologyIpsc Generation +13

Inhibition of Hepatocyte Growth Factor Induction in Human Dermal Fibroblasts by Tryptanthrin

Takahiro Motoki, Yoichiro Takami, Yasuyuki Yagi, +3

Biological and Pharmaceutical Bulletin

Transgenic expression of osteoactivin in the liver attenuates hepatic fibrosis in rats

Hiroo Abe, Hirofumi Uto, Yoichiro Takami, +8

Biochemical and Biophysical Research Communications

InflammationFibrosisLiver FibrosisHepatologyLiver Physiology +13

Liver regeneration after partial hepatectomy in rat is more impaired in a steatotic liver induced by dietary fructose compared to dietary fat

Shirou Tanoue, Hirofumi Uto, Ryo Kumamoto, +9

Biochemical and Biophysical Research Communications

NutritionHepatologyBiliary TractLiver PhysiologyLiver Regeneration +10

Clinical proteomics for liver disease: a promising approach for discovery of novel biomarkers

Hirofumi Uto, Shuji Kanmura, Yoichiro Takami, +1

Proteome Science

ImmunologyPathologyHepatic FibrosisFatty Liver DiseaseProteomic Technology +26

Expression of glycoprotein nonmetastatic melanoma protein B in macrophages infiltrating injured mucosa is associated with the severity of experimental colitis in mice

Fumisato Sasaki, Kotaro Kumagai, Hirofumi Uto, +11

Molecular Medicine Reports

Chronic Inflammatory DiseasesImmunologyImmune RegulationPathologyInnate Immunity +18

Synergistic induction of hepatocyte growth factor in human skin fibroblasts by the inflammatory cytokines interleukin-1 and interferon-γ

Yoichiro Takami, Takahiro Motoki, Itaru Yamamoto, +1

Biochemical and Biophysical Research Communications

Human GrowthImmune RegulationImmunologyPathologyCell Proliferation +17

Human neutrophil peptide-1 aggravates dextran sulfate sodium-induced colitis

Shinichi Hashimoto, Hirofumi Uto, Shuji Kanmura, +11

Inflammatory Bowel Diseases

Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M<i>in vivo</i>

Kenichiro Kudo, Kadoaki Ohashi, Go Makimoto, +14

Molecular Oncology