Dermcidin: a novel human antibiotic peptide secreted by sweat glands

Birgit Schittek, Rainer Hipfel, Birgit Sauer, +9

Nature Immunology

AntibioticsMedicineAntimicrobial ChemotherapyMicrobiologyDermatology +6

Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions

Siegbert Rieg, Claus Garbe, Birgit Sauer, +2

British Journal of Dermatology

Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors

Katharina Bitschar, Birgit Sauer, Jule Focken, +11

Nature Communications

The increased expression of Y box‐binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance

Birgit Schittek, Karin Psenner, Birgit Sauer, +3

International Journal of Cancer

Melanoma MetastasesCell DeathIncreased ExpressionCancer BiologyTumor Biology +16

β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

Tobias Sinnberg, Moritz Menzel, Daniel Ewerth, +5

PLoS ONE

Scid Mouse ModelTumor GrowthMedicineMelanomaCancer Cell Biology +13

Suppression of Casein Kinase 1α in Melanoma Cells Induces a Switch in β-Catenin Signaling to Promote Metastasis

Tobias Sinnberg, Moritz Menzel, Susanne Kaesler, +6

Cancer Research

Define Ck1alphaCell DeathCancer BiologyMelanoma CellsTumor Biology +15

MAPK and PI3K/AKT mediated YB‐1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop

Tobias Sinnberg, Birgit Sauer, Per Sonne Holm, +4

Experimental Dermatology

Melanoma ProgressionCell ProliferationCancer BiologyTumor BiologyMelanoma Cells +18

Staphylococcus aureus Skin Colonization Is Enhanced by the Interaction of Neutrophil Extracellular Traps with Keratinocytes

Katharina Bitschar, Lena Staudenmaier, Laura Klink, +11

Journal of Investigative Dermatology

Neutrophil Extracellular TrapsCutaneous BiologyWound InfectionWound HealingMicrobiology +6

YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT

Corinna Kosnopfel, Tobias Sinnberg, Birgit Sauer, +10

Molecular Cancer Research

Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase

Corinna Kosnopfel, Tobias Sinnberg, Birgit Sauer, +7

Oncotarget

Melanoma TherapyClinical AvailabilityMedicineReceptor Tyrosine KinaseMelanoma +9