Wild-Type <i>BRAF</i> Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

Federica Di Nicolantonio, Miriam Martini, Francesca Molinari, +8

Journal of Clinical Oncology

Kras MutationsGastrointestinal OncologyMedicineBraf MutationsImmunology +11

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

Wendy De Roock, Derek J. Jonker, Federica Di Nicolantonio, +15

JAMA

EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer

Vito Amodio, Rona Yaeger, Pamela Arcella, +26

Cancer Discovery

Adaptive mutability of colorectal cancers in response to targeted therapies

Mariangela Russo, Giovanni Crisafulli, Alberto Sogari, +20

Science

PathologyCancer BiologyTumor BiologyDrug ResistanceOncology +14

Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

Federica Di Nicolantonio, Sabrina Arena, Josep Tabernero, +15

Journal of Clinical Investigation

Cancer BiologyCellular PhysiologyTumor BiologySignaling PathwayReceptor Tyrosine Kinase +14

In vitro antibacterial activity of some aliphatic aldehydes from<i>Olea europaea</i>L.

Giuseppe Bisignano, Maria Grazia LaganÃ, Domenico Trombetta, +5

FEMS Microbiology Letters

Bioorganic ChemistryOrganic ChemistryPolyphenolicsDrug ResistanceFood Chemistry +17

Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer

Sandra Misale, Sabrina Arena, Simona Lamba, +14

Science Translational Medicine

Emergence of Multiple <i>EGFR</i> Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

Sabrina Arena, Beatríz Bellosillo, Giulia Siravegna, +22

Clinical Cancer Research

High-dose vitamin C enhances cancer immunotherapy

Alessandro Magrì, Giovanni Germano, Annalisa Lorenzato, +12

Science Translational Medicine

Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer

Beth O. Van Emburgh, Sabrina Arena, Giulia Siravegna, +19

Nature Communications

Crc SamplesColorectal CancersMedicineImmunologyCrc Patients +10