Rima Al‐awar

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Jiajun Zhu, Morgan A. Sammons, Greg Donahue et al. · Nature · 2015 · 482 citations · Full text

Cancer Research, Chromatin, Chromatin Remodeling +10

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Alicia M. Cole, Zezhou Wang, Étienne Coyaud et al. · Cancer Cell · 2015 · 340 citations · Full text

Hematological Malignancy, Mitochondrial Function, Mitochondrial Protease Clpp +10

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Wenyu Yu, Emma J. Chory, Amy K. Wernimont et al. · Nature Communications · 2012 · 283 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +8

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik et al. · Nature Chemical Biology · 2015 · 282 citations · Full text

Hematological Malignancy, Medicine, Pharmacology +4

( <i>R</i> )-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

Dalia Baršytė-Lovejoy, Fengling Li, Menno J. Oudhoff et al. · Proceedings of the National Academy of Sciences · 2014 · 188 citations · Full text