A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body

Yoshitada Sakai, Masahiko Miwa, Keisuke Oe, +7

PLoS ONE

Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells

Shingo Miyazaki, Kenichiro Kakutani, Takashi Yurube, +11

Arthritis Research & Therapy

Oxidative stress‐induced apoptosis and matrix loss of chondrocytes is inhibited by eicosapentaenoic acid

S. Sakata, Shinya Hayashi, Takaaki Fujishiro, +11

Journal of Orthopaedic Research®

The effect of transcutaneous application of carbon dioxide (CO2) on skeletal muscle

Keisuke Oe, Takeshi Ueha, Yoshitada Sakai, +7

Biochemical and Biophysical Research Communications

Carbon DioxideMuscle PhysiologyMuscle FunctionMuscle InjurySkeletal Muscle +7

P21 Deficiency Delays Regeneration of Skeletal Muscular Tissue

Nobuaki Chinzei, Shinya Hayashi, Takeshi Ueha, +9

PLoS ONE

Muscle FunctionCell ProliferationCytoskeletonCell CycleCellular Physiology +15

Regulation of Mitochondrial Proliferation by PGC-1α Induces Cellular Apoptosis in Musculoskeletal Malignancies

Yasuo Onishi, Takeshi Ueha, Teruya Kawamoto, +6

Scientific Reports

Age-Related Differences in Anterior Cruciate Ligament Remnant Vascular-Derived Cells

Atsuo Uefuji, Tomoyuki Matsumoto, Takehiko Matsushita, +4

The American Journal of Sports Medicine

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

Masayuki Morishita, Teruya Kawamoto, Hitomi Hara, +9

International Journal of Oncology

MitophagyHuman Osteosarcoma CellsApoptosisCell DeathPathology +20

Topical Cutaneous CO2 Application by Means of a Novel Hydrogel Accelerates Fracture Repair in Rats

Takaaki Koga, Takahiro Niikura, Sang Yang Lee, +7

Journal of Bone and Joint Surgery

Effect of local application of transcutaneous carbon dioxide on survival of random-pattern skin flaps

Izumi Saito, Takumi Hasegawa, Takeshi Ueha, +9

Journal of Plastic Reconstructive & Aesthetic Surgery

Local ApplicationTranscutaneous Carbon DioxideDermal StructureScar PreventionSurgery +8