Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

Anne Louise Hansen, Gregory J. Buchan, Michael Rühl, +26

Proceedings of the National Academy of Sciences

ImmunologyPathologyInflammationAntiviral Drug DevelopmentSting Palmitoylation +16

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

Dontscho Kerjaschki, Zsuzsanna Bagó-Horváth, Margaretha Rudas, +34

Journal of Clinical Investigation

Circular DefectsBreast OncologyAngiogenesisDistant Organ MetastasisMedicine +13

Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol‐sensitive<scp>TRPC</scp>cation channels

Thorsten J. Maier, Markus Follmann, H‐W Kleemann, +9

British Journal of Pharmacology

Pharmacological Inhibition of Platelet-Tumor Cell Cross-Talk Prevents Platelet-Induced Overexpression of Cyclooxygenase-2 in HT29 Human Colon Carcinoma Cells

Melania Dovizio, Thorsten J. Maier, Sara Alberti, +8

Molecular Pharmacology

Inhibition of prostaglandin E ₂ synthesis by SC‐560 is independent of cyclooxygenase 1 inhibition

Christian Brenneis, Thorsten J. Maier, Ronald Schmidt, +5

The FASEB Journal

Aldo-keto ReductasePge2 SynthesisTnfalpha-induced Pge2 SynthesisImmunologyMolecular Pain +18

Electrophilic Fatty Acid Species Inhibit 5-Lipoxygenase and Attenuate Sepsis-Induced Pulmonary Inflammation

Khader Awwad, Svenja D. Steinbrink, Timo Frömel, +11

Antioxidants and Redox Signaling

Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment

Astrid Janssen, Thorsten J. Maier, Susanne Schiffmann, +4

European Journal of Pharmacology

Cell Cycle BlockAnti-inflammatoryMedicinePharmacologyColorectal Cancer +7

Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53

Sabine Grösch, Karin Schilling, Astrid Janssen, +3

Biochemical Pharmacology

Chemoprevention StrategyMedicineApoptosisPathologyCell Death +6

Dimethylcelecoxib inhibits prostaglandin E2 production

Ivonne Wobst, Susanne Schiffmann, Kerstin Birod, +5

Biochemical Pharmacology

Chemoprevention StrategyBiochemistryMedicineNatural SciencesProstaglandin E2 Production +4

p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells

Astrid Janssen, Susanne Schiffmann, Kerstin Birod, +4

Biochemical and Biophysical Research Communications

OncologyMedicineColorectal CancerPathologyPharmacotherapy +7