Weifang Shan

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

Chemoprevention Strategy, Immunology, Pharmacotherapy +19

Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2:  Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, S. David Kimball, Raj N. Misra et al. · Journal of Medicinal Chemistry · 2002 · 156 citations · Full text

Combinatorial Chemistry, Drug Target, Cdk2 Protein +20

Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors

Ashvinikumar V. Gavai, Claude Quesnelle, Derek Norris et al. · ACS Medicinal Chemistry Letters · 2015 · 88 citations · Full text

Solid Tumors, Pharmacotherapy, Tumor Biology +18

1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues

Raj N. Misra, Hai-yun Xiao, David B. Rawlins et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 69 citations · Full text

Cyclin-dependent Kinases, Heterocyclic, Biochemistry +4

Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists

Mark Salvati, Aaron Balog, Weifang Shan et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 61 citations · Full text

Combinatorial Chemistry, Androgen Receptor Antagonists, Medicinal Chemistry +8