David B. Rawlins

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

Brian Zambrowicz, J Freiman, Phil Brown et al. · Clinical Pharmacology & Therapeutics · 2012 · 239 citations · Full text

Medicine, Endocrinology, Pharmacology +17

The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor

Paul A. Wender, Neil F. Badham, Simon P. Conway et al. · Journal of the American Chemical Society · 1997 · 172 citations

Natural Sciences, Chemistry, Drug Discovery +5

Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2:  Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, S. David Kimball, Raj N. Misra et al. · Journal of Medicinal Chemistry · 2002 · 157 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma

Bryce A. Harrison, N. Andrew Whitlock, Michael Voronkov et al. · Journal of Medicinal Chemistry · 2009 · 77 citations · Full text

Medicine, Ophthalmology, Pharmacology +14