Jonathan Cairns

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

Biola M. Javierre, Oliver S. Burren, Steven P. Wilder et al. · Cell · 2016 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Jonathan Cairns, Paula Freire-Pritchett, Steven Wingett et al. · Genome biology · 2016 · 464 citations · Full text

Life Sciences, Bioinformatics, Genetics +13

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity

Jacqueline H. L. Fok, Antonio Ramos‐Montoya, Mercedes Vázquez–Chantada et al. · Nature Communications · 2019 · 334 citations · Full text

Medicine, Oncology, Radiation Oncology +17

Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation

Adam J. Rubin, Brook C. Barajas, Mayra Furlan-Magaril et al. · Nature Genetics · 2017 · 325 citations

Life Sciences, Developmental Biology, Molecular Biology +14

Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation

Rasmus Siersbæk, Jesper Grud Skat Madsen, Biola M. Javierre et al. · Molecular Cell · 2017 · 267 citations

Life Sciences, Cell Biology, Molecular Biology +16