Loren Kinman

Lipid–Drug Association Enhanced HIV-1 Protease Inhibitor Indinavir Localization in Lymphoid Tissues and Viral Load Reduction: A Proof of Concept Study in HIV-2287-Infected Macaques

Loren Kinman, Scott J. Brodie, Che Chung Tsai et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 2003 · 81 citations

Immunology, Concept Study, Antiviral Drug +17

Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid

Amal Kaddoumi, Sung-Up Choi, Loren Kinman et al. · Drug Metabolism and Disposition · 2007 · 59 citations

Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma

John C. Kraft, Lisa A. McConnachie, Josefin Koehn et al. · AIDS · 2017 · 49 citations · Full text

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation

John C. Kraft, Lisa A. McConnachie, Josefin Koehn et al. · Journal of Controlled Release · 2018 · 48 citations · Full text

Nanomedicine, Mechanism-based Pharmacokinetic, Medicine +8

Long-Acting Profile of 4 Drugs in 1 Anti-HIV Nanosuspension in Nonhuman Primates for 5 Weeks After a Single Subcutaneous Injection

Lisa A. McConnachie, Loren Kinman, Josefin Koehn et al. · Journal of Pharmaceutical Sciences · 2018 · 39 citations

Nanomedicine, Engineering, Single Subcutaneous Injection +13