Josefin Koehn

Anti-HIV Drug-Combination Nanoparticles Enhance Plasma Drug Exposure Duration as Well as Triple-Drug Combination Levels in Cells Within Lymph Nodes and Blood in Primates

Jennifer Freeling, Josefin Koehn, Cuiling Shu et al. · AIDS Research and Human Retroviruses · 2014 · 81 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood

Jennifer Freeling, Josefin Koehn, Cuiling Shu et al. · AIDS · 2014 · 67 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma

John C. Kraft, Lisa A. McConnachie, Josefin Koehn et al. · AIDS · 2017 · 50 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation

John C. Kraft, Lisa A. McConnachie, Josefin Koehn et al. · Journal of Controlled Release · 2018 · 48 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Three HIV Drugs, Atazanavir, Ritonavir, and Tenofovir, Coformulated in Drug-Combination Nanoparticles Exhibit Long-Acting and Lymphocyte-Targeting Properties in Nonhuman Primates

Simone Perazzolo, Laura M. Shireman, Josefin Koehn et al. · Journal of Pharmaceutical Sciences · 2018 · 44 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17