Frédéric Villard

An automated microseed matrix-screening method for protein crystallization

A. D’Arcy, Frédéric Villard, M. Marsh · Acta Crystallographica Section D Biological Crystallography · 2007 · 210 citations

Engineering, Biomolecular Structure Prediction, Protein Phase Separation +16

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans

Alexander W. Koch, Nikolaus Schiering, Samu Melkko et al. · Blood · 2019 · 119 citations · Full text

Structural Determinants of MALT1 Protease Activity

Christian Wiesmann, Lukas Leder, Jutta Blank et al. · Journal of Molecular Biology · 2012 · 94 citations · Full text

Lymphocyte Development, Immune Regulation, Proteasome +25

Structure of neprilysin in complex with the active metabolite of sacubitril

Nikolaus Schiering, A. D’Arcy, Frédéric Villard et al. · Scientific Reports · 2016 · 66 citations · Full text

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

Jean Quancard, Théo Klein, Shan‐Yu Fung et al. · Nature Chemical Biology · 2019 · 65 citations

Autoimmune Disease, Immunodeficient Patient, Immunodeficiencies +11