Mark J. Chicarelli - Concepedia

Author

Mark J. Chicarelli

Array BioPharma (United States)

Also Known As

Mark Chicarelli, Mark J Chicarelli, Mark J. Chicarelli, Mark Joseph Chicarelli

Publications

823

Citations

H-Index

Concepts

All Affiliations

Array BioPharma (United States)Mirati Therapeutics (United States)Amgen (United States)

About

Mark J. Chicarelli is an author at Array BioPharma (United States) specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	141
2	Biochemistry	5	5	116
3	Natural Sciences	4	4	97
4	Health Sciences	1	1	19
5	Biomolecular Engineering	1	1	32

Mark J. Chicarelli

Publications

804

Citations

H-Index

Page 1

	Year	Citations
Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer Jay B. Fell, John P. Fischer, Brian R. Baer, Journal of Medicinal Chemistry	2020	559
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity Jay B. Fell, John P. Fischer, Brian R. Baer, ACS Medicinal Chemistry Letters	2018	104
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2 James F. Blake, John J. Gaudino, Jason De Meese, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicine	2014	39
Identification of a New Class of Glucokinase Activators through Structure-Based Design Ronald J. Hinklin, Steven A. Boyd, Mark J. Chicarelli, Journal of Medicinal Chemistry Protein AssemblyGlycobiologyInsulin SignalingEnzyme Kinetic ParametersStructure-based Design	2013	32
Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo Kurtis D. Davies, Michael Humphries, Francis X. Sullivan, Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics Tumor BiologyOncologySingle-agent InhibitionChk1 Is AntiproliferativeChemoprevention Strategy	2011	25
Characterization of a Novel Glucokinase Activator in Rat and Mouse Models Min Lü, Pingping Li, Gautam Bandyopadhyay, PLoS ONE Glucose HomeostasisCellular PhysiologyInsulin SignalingMetabolic SyndromeMouse Glucokinase	2014	19
C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators Xiaohui Du, Ronald J. Hinklin, Yumei Xiong, ACS Medicinal Chemistry Letters Medicinal ChemistryBioorganic ChemistryBiochemistryMedicineNatural Sciences	2014	15
Abstract B30: Structure-based drug discovery of MRTX1257, a selective, covalent KRAS G12C inhibitor with oral activity in animal models of cancer Matthew A. Marx, Brian R. Baer, Joshua A. Ballard, Molecular Cancer Research Drug TargetCyanomethyl GroupAbstract B30Chemical BiologyPharmaceutical Chemistry	2020	11

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