John J. Gaudino - Concepedia

Author

John J. Gaudino

Array BioPharma (United States)ORCID

Also Known As

J. GAUDINO, J. Gaudino, J. J. GAUDINO, J. J. Gaudino, John Gaudino, John J. Gaudino

158

Publications

1.8K

Citations

H-Index

Concepts

All Affiliations

Array BioPharma (United States)University of Pittsburgh Mirati Therapeutics (United States)University of California, Los Angeles Cytel (United States)

About

John J. Gaudino is an author at Array BioPharma (United States) specializing in pharmacology, biochemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	11	12	435
2	Medicine	10	10	421
3	Natural Sciences	10	10	377
4	Engineering	9	9	522
5	Arts	1	1	211

John J. Gaudino

Publications

1.7K

Citations

H-Index

Page 1

	Year	Citations
Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer Jay B. Fell, John P. Fischer, Brian R. Baer, Journal of Medicinal Chemistry	2020	559
A general synthesis of 5-arylnicotinates Wayne J. Thompson, John J. Gaudino The Journal of Organic Chemistry EngineeringMedia StandardsDatabasesAltmetric Attention ScoreBibliometrics	1984	211
Discovery of (<i>S</i>)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1<i>H</i>-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1<i>H</i>)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development James F. Blake, Michael Burkard, Jocelyn Chan, Journal of Medicinal Chemistry Erk Kinase ActivityCellular PharmacologyTumor BiologyPre-clinical PharmacologyMolecular Pharmacology	2016	156
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity Jay B. Fell, John P. Fischer, Brian R. Baer, ACS Medicinal Chemistry Letters	2018	104
New approaches to enzyme regulators. Synthesis and enzymological activity of carbocyclic analogs of D-fructofuranose and D-fructofuranose-6-phosphate Craig S. Wilcox, John J. Gaudino Journal of the American Chemical Society EngineeringNew ApproachesAltmetric Attention ScoreChemical BiologyEnzymatic Modification	1986	92
Solid phase synthesis of 1,4-benzodiazepine-2,5-diones John P. Mayer, Jingwen Zhang, Kirsten Bjergårde, Tetrahedron Letters Organic ChemistrySolid Phase SynthesisChemistryHeterocycle ChemistrySynthetic Chemistry	1996	91
A convenient method for the synthesis of α-Ketoesters from aldehydes David Horne, John J. Gaudino, Wayne J. Thompson Tetrahedron Letters EngineeringConvenient MethodOrganic ChemistryChemistrySynthesis Method	1984	48
Synthesis of bioactive sialosides Yukishige Ito, John J. Gaudino, James C. Paulson Pure and Applied Chemistry PharmacologySynthetic ChemistryBioactive SialosidesNatural Product Synthesis	1993	44
Discovery of Highly Potent, Selective, and Efficacious Small Molecule Inhibitors of ERK1/2 Li Ren, Jonas Grina, David Moreno‐Mateos, Journal of Medicinal Chemistry Chemoprevention StrategyPharmacotherapyChemical BiologyTumor BiologyMedicinal Chemistry	2015	42
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2 James F. Blake, John J. Gaudino, Jason De Meese, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicine	2014	39

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