Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis

Yoichiro Kitajima, Hirokazu Takahashi, Takumi Akiyama, +9

Journal of Gastroenterology

Metabolic SyndromeNutritionLiver PhysiologyPhysiologyLiver Cirrhosis +7

Severity of non‐alcoholic steatohepatitis is associated with substitution of adipose tissue in skeletal muscle

Yoichiro Kitajima, Hideyuki Hyogo, Yoshio Sumida, +10

Journal of Gastroenterology and Hepatology

The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease

Yuichiro Eguchi, Toshihiko Mizuta, Yoshio Sumida, +18

Journal of Gastroenterology

InflammationMetabolic SyndromeObesityMetabolic Associated SteatohepatitisPathological Role +13

Glucagon-Like Peptide-1 Receptor Agonist Prevented the Progression of Hepatocellular Carcinoma in a Mouse Model of Nonalcoholic Steatohepatitis

Motoyasu Kojima, Hirokazu Takahashi, Takuya Kuwashiro, +8

International Journal of Molecular Sciences

PathologyFatty Liver DiseaseControl MiceInsulin SignalingGastrointestinal Peptide Hormone +21

Prediction of Nonalcoholic Fatty Liver Disease Using Noninvasive and Non-Imaging Procedures in Japanese Health Checkup Examinees

Kenichiro Murayama, Michiaki Okada, Kenichi Tanaka, +16

Diagnostics

Comparison of Efficacy and Safety of Atezolizumab Plus Bevacizumab and Lenvatinib as First-Line Therapy for Unresectable Hepatocellular Carcinoma: A Propensity Score Matching Analysis

Takashi Niizeki, Takayuki Tokunaga, Yuko Takami, +27

Targeted Oncology

Post-challenge hyperglycemia is a significant risk factor for the development of hepatocellular carcinoma in patients with chronic hepatitis C

Toshihiko Mizuta, Yuichiro Eguchi, Yasunori Kawaguchi, +9

Journal of Gastroenterology

HepatologyHepatitis CViral HepatitisLiver PhysiologyDiabetes +9

Discordant pathological diagnosis of non‐alcoholic fatty liver disease: A prospective multicenter study

Takuya Kuwashiro, Hirokazu Takahashi, Hideyuki Hyogo, +14

JGH Open

Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and its Inhibition by Vitamin K2 in Hepatocellular Carcinoma Cells

Jinghe Xia, Iwata Ozaki, Sachiko Matsuhashi, +4

International Journal of Molecular Sciences

Whole-Body Insulin Sensitivity Index Is a Highly Specific Predictive Marker for Virological Response to Peginterferon Plus Ribavirin Therapy in Chronic Hepatitis C Patients with Genotype 1b and High Viral Load

Toshihiko Mizuta, Yasunori Kawaguchi, Yuichiro Eguchi, +8

Digestive Diseases and Sciences

HepatologyHepatitis CViral HepatitisDiabetesAntiviral Therapy +6