Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity

Wei Ying, Yun Sok Lee, Yi Dong, +11

Cell Metabolism

ObesityMetabolic SyndromeInflammationInsulin SignalingIslet-resident Macrophages Leads +11

Critical Role of Connexin 43 in Secondary Expansion of Traumatic Spinal Cord Injury

Chunlan Huang, Xiaoning Han, Xi Li, +10

Journal of Neuroscience

Neurological InjurySpinal DisorderCellular PhysiologySocial SciencesNeuroinflammation +19

Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice

Stephanos Kyrkanides, Ross H. Tallents, Jen‐nie H. Miller, +6

Journal of Neuroinflammation

PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness

Meixiang Yang, Dan Li, Zai Chang, +3

The Journal of Experimental Medicine

Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075

Yudong Ji, Zhenlong Luo, Hong Gao, +9

Nature Metabolism

Extracellular MicrovesiclesInsulin SignalingObesityMetabolic SyndromeObese Mice +14

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation

Meixiang Yang, Shasha Chen, Juan Du, +13

Nature Communications

Combined deficiency of SLAMF8 and SLAMF9 prevents endotoxin-induced liver inflammation by downregulating TLR4 expression on macrophages

Xiaokang Zeng, Guangao Liu, Wanwen Peng, +6

Cellular and Molecular Immunology

InflammationCytokineImmune Cell DevelopmentAutophagyImmunology +8

Reduced Expression of Galectin-9 Contributes to a Poor Outcome in Colon Cancer by Inhibiting NK Cell Chemotaxis Partially through the Rho/ROCK1 Signaling Pathway

Yang Wang, Jintang Sun, Chao Ma, +15

PLoS ONE

Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers

Bowen Sun, Seth Mason, Robert Wilson, +9

Oncogene

The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education

Shasha Chen, Meixiang Yang, Juan Du, +7

Immunity

Natural Killer CellsSignal TransductionAdaptive Immune SystemImmunologyImmunologic Mechanism +9