Concepedia

Michael Czarniecki

MC

Statistics

Publications

43

Citations

2.2K

H-Index

27

Active since

1976

Affiliations

AIL Research (United States)(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Duke University

Michael Czarniecki is an author at AIL Research (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.

Publications per year

1976–2012

43

Publications

43

Improved acylation rates within cyclodextrin complexes from flexible capping of the cyclodextrin and from adjustment of the substrate geometry

Ronald Breslow, Michael Czarniecki, Jack Emert et al. · Journal of the American Chemical Society · 1980 · 204 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

Claudio N. Cavasotto, Andrew Orry, Nicholas Murgolo et al. · Journal of Medicinal Chemistry · 2008 · 169 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 154 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Carbon-13 nuclear magnetic resonance spin-lattice relaxation in the N-acylneuraminic acids. Probes for internal dynamics and conformational analysis

Michael Czarniecki, Edward R. Thornton · Journal of the American Chemical Society · 1977 · 131 citations

Natural Sciences, Biophysics, Chemistry +17

Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents

Samuel Chackalamannil, Yan Xia, William J. Greenlee et al. · Journal of Medicinal Chemistry · 2005 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

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