Michael Czarniecki

Improved acylation rates within cyclodextrin complexes from flexible capping of the cyclodextrin and from adjustment of the substrate geometry

Ronald Breslow, Michael Czarniecki, Jack Emert et al. · Journal of the American Chemical Society · 1980 · 204 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

Claudio N. Cavasotto, Andrew Orry, Nicholas Murgolo et al. · Journal of Medicinal Chemistry · 2008 · 169 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 154 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Carbon-13 nuclear magnetic resonance spin-lattice relaxation in the N-acylneuraminic acids. Probes for internal dynamics and conformational analysis

Michael Czarniecki, Edward R. Thornton · Journal of the American Chemical Society · 1977 · 131 citations

Natural Sciences, Biophysics, Chemistry +17

Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents

Samuel Chackalamannil, Yan Xia, William J. Greenlee et al. · Journal of Medicinal Chemistry · 2005 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17