Laura A. Jaenicke

Ubiquitylation of the amino terminus of Myc by SCFβ-TrCP antagonizes SCFFbw7-mediated turnover

Nikita Popov, Christina Schülein, Laura A. Jaenicke et al. · Nature Cell Biology · 2010 · 152 citations

Protein Function, Signal Transduction, Protein Expression +11

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

Markus E. Diefenbacher, Nikita Popov, Sophia M. Blake et al. · Journal of Clinical Investigation · 2014 · 152 citations · Full text

Tumor Biology, Usp28 Deletion, Gastrointestinal Oncology +14

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer

Björn von Eyß, Laura A. Jaenicke, Roderik M. Kortlever et al. · Cancer Cell · 2015 · 141 citations · Full text

Breast Oncology, Signal Transduction, Mitochondrial Function +9

Tumor cell‐specific inhibition of <scp>MYC</scp> function using small molecule inhibitors of the <scp>HUWE</scp> 1 ubiquitin ligase

Stefanie Peter, Jennyfer Bultinck, Kevin Myant et al. · EMBO Molecular Medicine · 2014 · 119 citations · Full text

Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation

Laura A. Jaenicke, Björn von Eyß, Anne Carstensen et al. · Molecular Cell · 2015 · 114 citations · Full text

Transcriptional Regulation, Ubiquitin-dependent Turnover, Cell Regulation +9