Roland Selig

Design, Synthesis, and Biological Evaluation of Novel 3-Aryl-4-(1<i>H</i>-indole-3yl)-1,5-dihydro-2<i>H</i>-pyrrole-2-ones as Vascular Endothelial Growth Factor Receptor (VEGF-R) Inhibitors

Christian Peifer, Roland Selig, K. Kinkel et al. · Journal of Medicinal Chemistry · 2008 · 92 citations · Full text

Pyrrole-2-one 2, Amide 2, Chemical Biology +18

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Stefan Zwirner, Anan Abu Rmilah, Sabrina Klotz et al. · Cell · 2024 · 46 citations · Full text

A Frozen Analogue Approach to Aminopyridinylimidazoles Leading to Novel and Promising p38 MAP Kinase Inhibitors

Roland Selig, Márcia Inês Goettert, Verena Schattel et al. · Journal of Medicinal Chemistry · 2012 · 29 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +19

Design and synthesis of 1H-pyrazolo[3,4-b]pyridines targeting mitogen-activated protein kinase kinase 4 (MKK4) - A promising target for liver regeneration

Bent Pfaffenrot, Philip Klövekorn, Michael Juchum et al. · European Journal of Medicinal Chemistry · 2021 · 22 citations · Full text

Medicinal Chemistry, Natural Sciences, Drug Discovery +9

Fluorescence polarization binding assay to develop inhibitors of inactive p38α mitogen-activated protein kinase

Lenka Munoz, Roland Selig, Yiu To Yeung et al. · Analytical Biochemistry · 2010 · 20 citations

Molecular Pharmacology, Signal Transduction, Signaling Pathway +11