Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

William G. Devine, Jennifer L. Woodring, Uma Swaminathan, +10

Journal of Medicinal Chemistry

Antiparasitic AgentMalariaImmunologyPathologyLead Identification +18

Antitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth

Emanuele Amata, Joel W. Beatty, Zeke T. Clements, +10

Journal of Medicinal Chemistry

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

Gautam Patel, Norma Roncal, Patricia Lee, +5

MedChemComm

A high-efficiency microfluidic device for size-selective trapping and sorting

Jinho Kim, Jessey Erath, Ana Rodrı́guez, +1

Lab on a Chip

Imaging and Identification of Waterborne Parasites Using a Chip-Scale Microscope

Seung Ah Lee, Jessey Erath, Guoan Zheng, +5

PLoS ONE

Parasitic DiseaseEngineeringPathogen DetectionMicroscopyWaterborne Parasites +13

Evaluation of aromatic 6-substituted thienopyrimidines as scaffolds against parasites that cause trypanosomiasis, leishmaniasis, and malaria

Jennifer L. Woodring, Gautam Patel, Jessey Erath, +7

MedChemComm

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Emanuele Amata, Hualin Simon Xi, Gonzalo Colmenarejo, +12

ACS Infectious Diseases

Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation

Jennifer L. Woodring, Kelly A. Bachovchin, Kimberly G. Brady, +7

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryAntiparasitic AgentNatural SciencesMedicine +8

Plasmodium falciparum translational machinery condones polyadenosine repeats

Slavica Pavlovic Djuranovic, Jessey Erath, Ryan J. Andrews, +7

eLife

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites

William G. Devine, Sarah M. Thomas, Jessey Erath, +7

ACS Medicinal Chemistry Letters