Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes

Ana Herrero, Adán Pinto, Paula Colón‐Bolea, +18

Cancer Cell

Cell RegulationReceptor Tyrosine KinaseRas-erk Pathway OncogenesCell BiologyMedicine +4

Distinct Utilization of Effectors and Biological Outcomes Resulting from Site-Specific Ras Activation: Ras Functions in Lipid Rafts and Golgi Complex Are Dispensable for Proliferation and Transformation

David Matallanas, Victoria Sanz‐Moreno, Imanol Arozarena, +5

Molecular and Cellular Biology

Ras Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins

Berta Casar, Imanol Arozarena, Victoria Sanz‐Moreno, +6

Molecular and Cellular Biology

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

Fernando Calvo, Victoria Sanz‐Moreno, Lorena Agudo‐Ibáñez, +4

Nature Cell Biology

Signal TransductionCell RegulationCell SignalingCytoskeletal DynamicsMedicine +8

An Integrated Global Analysis of Compartmentalized HRAS Signaling

Tapesh Santra, Ana Herrero, Javier Rodríguez, +11

Cell Reports

Molecular BiologyGlobal InformationCellular PhysiologySignaling PathwayAutophagy +16

Association of MHC Class I Related Gene B (MICB) to Celiac Disease

Segundo González, Antonio López‐Vázquez, Dolores Fuentes, +5

The American Journal of Gastroenterology

H-Ras Distribution and Signaling in Plasma Membrane Microdomains Are Regulated by Acylation and Deacylation Events

Lorena Agudo‐Ibáñez, Ana Herrero, Mariano Barbacid, +1

Molecular and Cellular Biology

Deacylation EventsProteinlipid InteractionH-ras DistributionCellular PhysiologyMembrane Transport +14

Transcriptomal profiling of site-specific Ras signals

Lorena Agudo‐Ibáñez, F. Rueda Núñez, Fernando Calvo, +3

Cellular Signalling

Transcriptomal ProfilingFunctional GenomicsComputational BiologySignal RecognitionTranscriptomics Technology +5

Defined spatiotemporal features of RAS-ERK signals dictate cell fate in MCF-7 mammary epithelial cells

Ana Herrero, Berta Casar, Paula Colón‐Bolea, +2

Molecular Biology of the Cell

Cell DeathSpatiotemporal FeaturesCytoskeletonCell GrowthCell Fate +25

ERK2 stimulates <i>MYC</i> transcription by anchoring CDK9 to the <i>MYC</i> promoter in a kinase activity–independent manner

Lorena Agudo‐Ibáñez, Marta Morante, Lucia García-Gutiérrez, +5

Science Signaling