Alexandra Ehrens

Preclinical development of an oral anti- <i>Wolbachia</i> macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

Mark J. Taylor, Thomas W von Geldern, Louise Ford et al. · Science Translational Medicine · 2019 · 85 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

AWZ1066S, a highly specific anti- <i>Wolbachia</i> drug candidate for a short-course treatment of filariasis

W. David Hong, Farid Benayoud, Gemma L. Nixon et al. · Proceedings of the National Academy of Sciences · 2019 · 71 citations · Full text

Veterinary Medicine, Infectious Disease Control, Infectious Diseases +17

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections

Malina A. Bakowski, Roohollah Kazem Shiroodi, Renhe Liu et al. · Science Translational Medicine · 2019 · 45 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Boron-Pleuromutilins as Anti-<i>Wolbachia</i> Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

Robert T. Jacobs, Christopher S. Lunde, Yvonne R. Freund et al. · Journal of Medicinal Chemistry · 2019 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro

Marc P. Hübner, Coralie Martin, Sabine Specht et al. · PLoS neglected tropical diseases · 2020 · 43 citations · Full text

Veterinary Medicine, Infectious Diseases, Veterinary Parasitology +17