CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

Rebecca C. Larson, Michael C. Kann, Stefanie R. Bailey, +17

Nature

Liquid TumoursCancer ImmunosurveillanceImmunologyTumor ImmunityCell Death +9

Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, +13

Cancer Cell

Hematological MalignancyCell TherapyAcute Myeloid LeukemiaImmunologyAdult T-cell Leukemia-lymphoma +4

Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy

Carmela Passaro, Quazim A. Alayo, Isabel DeLaura, +15

Clinical Cancer Research

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

Marc Wehrli, Samantha Guinn, Filippo Birocchi, +36

Clinical Cancer Research

Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis

Harald Krenzlin, Prajna Behera, Viola Lorenz, +18

Journal of Clinical Investigation

AngiogenesisGliomaTumor GrowthMcmv ReactivationImmunology +10

Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

Marco Mineo, Shawn M. Lyons, Mykola Zdioruk, +20

Molecular Cell

Transcriptional RegulationLncrna Incr1 TranscribedImmunologyLong Non-coding RnaSmall Rna +6

Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1–dependent NK cell-mediated lysis of infected cells

Korneel Grauwet, Claudia Cantoni, Monica Parodi, +6

Proceedings of the National Academy of Sciences

Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses

Quazim A. Alayo, Hirotaka Ito, Carmela Passaro, +10

Scientific Reports

Comparative immune responses against Psoroptes ovis in two cattle breeds with different susceptibility to mange

Charlotte Sarre, Ana Isabel González-Hernández, Stefanie Van Coppernolle, +7

Veterinary Research

Suppression of NK cell-mediated cytotoxicity against PRRSV-infected porcine alveolar macrophages in vitro

Jun Cao, Korneel Grauwet, Ben Vermeulen, +4

Veterinary Microbiology

InflammationImmunologyViral PathogenesisAntiviral ResponseVirology +5